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07 SMILES CC(C)C(N(CCCN)C(=O)C1=CC=C(C)C=C1)C1=NC2=CC(Cl)=CC=C2C(=O)N1CC1=CC=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity
This modification effectively creates a structurally similar molecule that mimics the original ligand’s size
good photostability
Nature 2020
Azide-Dap(m-PEG4)-Val-Cit-OH Size:10mg 07 SMILES CC(C)C(N(CCCN)C(=O)C1=CC=C(C)C=C1)C1=NC2=CC(Cl)=CC=C2C(=O)N1CC1=CC=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine
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