Azide-Propionyl-Val-Ala-PAB(m-PEG8)-PNP DBCO including biomolecules containing azide groups

including biomolecules containing azide groups through copper catalyzed azide-alkyne cycloaddition (CuAAC)

821 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C46H74N8O17 Molecular Weight 1011

Product Name DOTA-tris(t-Bu)ester-PEG4-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C39H71N5O11 Molecular Weight 786

334 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCOCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Propionyl-Val-Ala-PAB(m-PEG8)-PNP DBCO including biomolecules containing azide groupsSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine