Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) crbn gov/ct2/show/NCT04191499 (accessed Mar 29

gov/ct2/show/NCT04191499 (accessed Mar 29

Product Name Lenalidomide-CO-C5-amine HCl Synonyms Lenalidomide-4'-CO-C5-amine HCl CAS Number 2284453-73-0 Related CAS Molecular Formula C19H25ClN4O4 Molecular Weight 408

47 Purity (HPLC) >= 95% Physical Appearance Light Yellow Solid Optical Properties n/a Solubility DMSO

Product Name Trametinib Synonyms CAS Number 871700-17-3 Related CAS Molecular Formula C26H23FIN5O4 Molecular Weight 615

Product Name tert-butyl 2-[4-(piperazin-1-yl)piperidin-1-yl]acetate Synonyms 1-Piperidineacetic acid

Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) crbn gov/ct2/show/NCT04191499 (accessed Mar 29SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further