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Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-amine 64 SMILES Cl

SKU: 36668143899

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Description

64 SMILES Cl

N-(dimethyl-d6)aniline Synonyms CAS Number n/a Related CAS Molecular Formula C9H12ClN Molecular Weight 175

Product Name Pomalidomide-C2-amine TFA Synonyms Pomalidomide-4'-C2-amine TFA CAS Number 1957235-67-4 Related CAS 1957235-66-3 (free base) Molecular Formula C17H17F3N4O6 Molecular Weight 430

Fitzgibbons

Chloroquinaxoline sulfonamide (CQS) share the same mechanism of action as Indisulam

Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-amine 64 SMILES ClSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate

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