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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP mpeg 314 SMILES O=C1N(CC2=C(NCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC)

SKU: 37752023769

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Description

314 SMILES O=C1N(CC2=C(NCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

692 Purity (HPLC) >= 95% Solubility DMSO

Product Name Phthalimidinoglutarimide-C3-O-C2-amine HCl Synonyms Phthalimidinoglutarimide-4'-C3-O-C2-amine HCl CAS Number 2093387-45-0 Related CAS Molecular Formula C18H24ClN3O4 Molecular Weight 381

Product Name Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C77H95FN12O24 Molecular Weight 1591

VHL-SNAP2-5C is a SNAP PROteolysis TArgeting Chimera (SNAP-PROTAC)

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP mpeg 314 SMILES O=C1N(CC2=C(NCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload

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