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Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP protac ligand Its high reactivity towards HOCl

SKU: 40089324216

4.3
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Description

Its high reactivity towards HOCl makes NBD-TM the probe of choice for HTS campaigns based on HOCl detection

65 SMILES [2H]C([2H])([2H])N(C1=C(F)C=CC=C1Cl)C([2H])([2H])[2H] Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

85 SMILES: Cl

The introduction of TMP-POM 7c

Product Name Phthalimidinoglutarimide-5'-C4-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C17H22ClN3O3 Molecular Weight 351

Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP protac ligand Its high reactivity towards HOClSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP

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