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DBCO-Dap(m-PEG4)-Val-Cit-OH Size:50mg which induces DNA damage by

SKU: 44794460038

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Description

which induces DNA damage by stabilizing the topoisomerase I–DNA complex

DMF Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

leading to cell-cycle arrest and subsequent apoptosis

178 SMILES [2H]C([2H])([2H])N1C(=O)C(=O)C2=CC=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

15 SMILES Cl

DBCO-Dap(m-PEG4)-Val-Cit-OH Size:50mg which induces DNA damage bySOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,

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