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Datasheet MSDS
diAcFAM is typically supplied as a cell-permeable ligand that
HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation
Nature 2020
as the acetylation masks the hydroxyl groups critical for fluorescein’s fluorescence
Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8)-PNP mal-hexanoyl Datasheet MSDSSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating
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